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1 The treatment regimens were AC every 3 weeks for four cycles followed by T every 3 weeks for four cycles AC T; 24 weeks; A plus T every 3 weeks for four cycles AT; 12 weeks; and T plus A plus C every 3 weeks for four cycles TAC; 12 weeks tadalista vs cialis Hence for drugs that are metabolized by CYP2D6 that is CYP2D6 substrates, certain individuals will eliminate these drugs quickly extensive metabolizers whilst others will do that slowly poor metabolizers